Research

Interdisciplinary Research Teams

Our scientific and engineering research focuses on bionanotechnology for enhanced public security and environmental safety. Of particular interest is the development of fundamental knowledge needed for field-deployable sensors that can monitor DNA fingerprinting and the presence of specific heavy metals, pathogens, and other environmental threats in real-time. This research is organized within the framework of Interdisciplinary Research Teams (IRTs). IRTs include faculty from different departments working towards a common research goal. The interdisciplinary nature of the research is enhanced by the  WVU Shared Research Facilities, which provide a research space where students, postdocs, faculty, and external users from different backgrounds work together.

Seed Projects

  • Seed 1: Environmental Sensing Using a Broadly Selective Aptamer (2010-2012)

    Principal Investigator (PI)
    Lisa Holland, Associate Professor, Department of Chemistry, WVU

    Co-Investigators (Co-PI)
    Letha Sooter, Assistant Professor, Department of Basic Pharmaceutical Sciences, WVU
    Yolanda Fintschenko, Labsmith

  • Seed 2: Electric Cell Impedance Sensing (ECIS) to Quantify Cytotoxicity of Nanomaterials to Human Epithelial Cells (2010-2011, merged with IRT 3)

    Principal Investigator (PI)
    Cerasela Zoica Dinu, Assistant Professor, Department of Chemical Engineering, WVU

    Co-Investigator (Co-PI)
    Yon Rojanasakul, Professor, Department of Basic Pharmaceutical Sciences, WVU

  • Seed 3: Detection of Mycotoxins using Graphene-Peptide Micro-Sensors Arrays (2011-2012)

    Principal Investigator (PI)
    Robin S. Hissam, Assistant Professor, Department of Chemical Engineering, WVU

    Co-Investigators (Co-PI)
    Edward M. Sabolsky, Assistant Professor, Department of Mechanical and Aerospace Engineering, WVU
    Charter D. Stinespring, Department of Chemical Engineering, WVU

  • Seed 4: Nanotopographical Effect of Substrates on Cellular Responses to Nanomaterials (2012-2013)

    Principal Investigator (PI)
    Yong Yang, Assistant Professor, Department of Chemical Engineering, WVU

    Co-Investigators (Co-PI)
    Pradeep P. Fulay, Professor, Associate Dean for Research, Department of Chemical Engineering, WVU
    Yon Rojanasakul, Professor, Department of Basic Pharmaceutical Sciences, WVU
    Liying Wang, Principal Investigator / Adjunct Professor, National Institute for Occupational Safety and Health (NIOSH) / School of Pharmacy, WVU

  • Seed 5: Theoretical Optimization of Single Biomolecule Deposition onto Nanoelectrode Arrays (2013-2014)

    Principal Investigator (PI)
    Blake Mertz, Assistant Professor, C. Eugene Bennett Department of Chemistry, WVU

    Co-Investigators (Co-PI)
    Peter Gannett, Professor, Department of Basic Pharmaceutical Sciences, WVU